Publications

Selected TrialNet Publications by University of Florida Authors.

2020

Comparing Beta Cell Preservation Across Clinical Trials in Recent-Onset Type 1 Diabetes.
Laura M. Jacobsen, Brian Bundy, Madison Greco, Desmond A. Schatz, Mark A. Atkinson, Todd M. Brusko, Clayton Mathews, Kevan C. Herold, Stephen E. Gitelman, Jeffrey P. Krischer, Michael J. Haller.
Diabetes Technology & Therapeutics. doi: 10.1089/dia.2020.0305. Epub 2020 Aug 24.
PubMed PMID: 32833543.

Slowed Metabolic Decline after One Year of Oral Insulin Treatment among Individuals at High Risk for Type 1 Diabetes in the Diabetes Prevention Trial-Type 1 and TrialNet Oral Insulin Prevention Trials.
Jay M. Sosenko, Jay S. Skyler, Kevan C. Herold, Desmond A. Schatz, Michael J. Haller, Alberto Pugliese, Mario Cleves, Susan Geyer, Lisa Rafkin, Della Matheson, Jerry P. Palmer, Type 1 Diabetes TrialNet Study Group.
Diabetes. doi: doi: 10.2337/db20-0166. Epub 2020 May 21.
PubMed PMID: 32439823.

Clinical Trial Data Validate the C-peptide Estimate Model in Type 1 Diabetes.
John M. Wentworth, Naiara G. Bediaga, Stephen E. Gitelman, Carmela Evans-Molina, Peter A. Gottlieb, Peter G. Colman, Michael J. Haller, Leonard C. Harrison.
Diabetologia. 2020 Apr 1;63(4):885-886. doi: 10.1007/s00125-020-05088-6. Epub 2020 Jan 26.
PubMed PMID: 31982961.

The Risk of Progression to Type 1 Diabetes is Highly Variable in Individuals with Multiple Autoantibodies Following Screening.
Laura M. Jacobsen, Laura Bocchino, Carmella Evans-Molina, Linda A. DiMeglio, Robin Goland, Darrell M. Wilson, Mark A. Atkinson, Tandy Aye, William E. Russell, John M. Wentworth, David Boulware, Susan M. Geyer, Jay M. Sosenko.
Diabetologia. 2020 Mar 1;63(3):588-596. doi: 10.1007/s00125-019-05047-w. Epub 2019 Nov 25.
PubMed PMID: 31768570. PMCID: PMC7229995.

Introducing the Endotype Concept to Address the Challenge of Disease Heterogeneity in Type 1 Diabetes.
Manuela Battaglia, Simi Ahmed, Mark S. Anderson, Mark A. Atkinson, Dorothy Becker, Polly J. Bingley, Emanuele Bosi, Todd M. Brusko, Linda
A. DiMeglio, Carmella Evans-Molina, Stephen E. Gitelman, Carla J. Greenbaum, Peter A. Gottlieb, Kevan C. Herold, Martin J. Hessner, Mikael Knip, Laura Jacobsen, Jeffrey P. Krischer, S. Alice Long, Markus Lundgren, Eoin F. McKinney, Noel G. Morgan, Richard A. Oram, Tomi Pastinen, Michael C. Peters, Alessandra Petrelli, Xiaoning Qian, Maria J. Redondo, Bart O. Roep, Desmond Schatz, David Skibinski, Mark Peakman.
Diabetes Care. 2020 Jan 1;43(1):5-12. doi: 10.2337/dc19-0880. Epub 2019 Nov 21.
PubMed PMID: 31753960. PMCID: PMC6925574.

2019

Who Is Enrolling? The Path to Monitoring in Type 1 Diabetes TrialNet’s Pathway to Prevention.
Emily K. Sims, Susan Geyer, Suzanne Bennett Johnson, Ingrid Libman, Laura M. Jacobsen, David Boulware, Lisa E. Rafkin, Della Matheson, Mark A. Atkinson, Henry Rodriguez, Maria Spall, Helena Elding Larsson, Diane K. Wherrett, Carla J. Greenbaum, Jeffrey P. Krischer, Linda A. DiMeglio, the Type 1 Diabetes TrialNet Study Group.
Diabetes Care. 2019 Dec 1;42(12):2228-2236. doi: 10.2337/dc19-0593. Epub 2019 Sep 26.
PubMed PMID: 31558546. PMCID: PMC6868467.

An Anti-CD3 Antibody, Teplizumab, in Relatives at Risk for Type 1 Diabetes.
Kevan C. Herold, Brian N. Bundy, S. Alice Long, Jeffrey A. Bluestone, Linda A. DiMeglio, Matthew J. Dufort, Stephen E. Gitelman, Peter A. Gottlieb, Jeffrey P. Krischer, Peter S. Linsley, Jennifer B. Marks, Wayne Moore, Antoinette M. Moran, Henry Rodriguez, William E. Russell, Desmond A. Schatz, Jay S. Skyler, Eva Tsalikian, Diane K. Wherrett, Anette-G Ziegler, and Carla J. Greenbaum, for the Type 1 Diabetes TrialNet Study Group.
The New England Journal of Medicine . doi: 10.1056/NEJMoa1902226. Epub 2019 Jun 9.
PubMed PMID: 31180194. PMCID: PMC6776880.

Low-Dose Anti-Thymocyte Globulin (ATG) Preserves C-Peptide and Reduces A1c in New-Onset Type 1 Diabetes: Two Year Clinical Trial Data. Michael J. Haller, S. Alice Long, Lori Blanchfield, Desmond A. Schatz, Jay S. Skyler, Jeffrey P. Krischer, Brian N. Bundy, Susan M. Geyer, Megan Warnock, Jessica L. Miller, Mark A. Atkinson, Dorothy J. Becker, David A. Baidal, Linda A. DiMeglio, Stephen E. Gitelman, Robin S. Goland, Peter A. Gottlieb, Kevan C. Herold, Jennifer B. Marks, Antoinette M. Moran, Henry Rodriguez, William E. Russell, Darrell M. Wilson, Carla J. Greenbaum, for the Type 1 Diabetes TrialNet ATG-GCSF Study Group.
Diabetes. 2019 Jun 1;68(6):1267-1276. doi: 10.2337/db19-0057. Epub 2019 Apr 9.
PubMed PMID: 30967424. PMCID: PMC6610026.

Relative Pancreas Volume is Reduced in First-Degree Relatives of Patients with Type 1 Diabetes.
Martha L. Campbell-Thompson, Stephanie L. Filipp, Joseph R. Grajo, Bimota Nambam, Richard Beegle, Erik H. Middlebrooks, Matthew J. Gurka, Mark A. Atkinson, Desmond A. Schatz, Michael J. Haller.
Diabetes Care. 2019 Feb 1;42(2):281-287. doi: 10.2337/dc18-1512. Epub 2018 Dec 14.
PubMed PMID: 30552130. PMCID: PMC6341284.

2018

Transcription Factor 7-Like 2 (TCF7L2) Gene Polymorphism and Progression From Single to Multiple Autoantibody Positivity in Individuals at Risk for Type 1 Diabetes.
Maria J. Redondo, Andrea K. Steck, Jay M. Sosenko, Mark S. Anderson, Peter Antinozzi, Aaron W. Michels, John M. Wentworth, Mark A. Atkinson, Alberto Pugliese, Susan M. Geyer, and the Type 1 Diabetes TrialNet Study Group.
Diabetes Care. 2018 Dec 1;21(12):2480-2486. doi: 10.2337/dc18-0861. Epub 2018 Oct 1.
PubMed PMID: 30275285. PMCID: PMC6245213.

Low-Dose Anti-Thymocyte Globulin (ATG) Preserves β-Cell Function and Improves HbA(1c) in New-Onset Type 1 Diabetes.
Michael J. Haller, Desmond A. Schatz, Jay S. Skyler, Jeffrey P. Krischer, Brian N. Bundy, Jessica L. Miller, Mark A. Atkinson, Dorothy J. Becker, David Baidal, Linda A. DiMeglio, Stephen E. Gitelman, Robin Goland, Peter A. Gottlieb, Kevan C. Herold, Jennifer B. Marks, Antoinette M. Moran, Henry Rodriguez, William Russell, Darrell M. Wilson, Carla J. Greenbaum, and the Type 1 Diabetes TrialNet ATG-GCSF Study Group. Diabetes Care. 2018 Sep 18;41(9):1917-1925. doi: 10.2337/dc18-0494. Epub 2018 Jul 16.
PubMed PMID: 30012675. PMCID: PMC6105329.

A Type 1 Diabetes Genetic Risk Score Predicts Progression of Islet Autoimmunity and Development of Type 1 Diabetes in Individuals at Risk. Maria J. Redondo, Susan M. Geyer, Andrea K. Steck, Seth Sharp, John M. Wentworth, Michael N. Weedon, Peter Antinozzi, Jay M. Sosenko, Mark A. Atkinson, Alberto Pugliese, Richard A. Oram, and the Type 1 Diabetes TrialNet Study Group.
Diabetes Care. 2018 Sep 1;41(9):1887-1894. doi: 10.2337/dc18-0087. Epub 2018 Jul 12.
PubMed PMID: 30002199. PMCID: PMC6105323.

Strength in Numbers: Opportunities for Enhancing the Development of Effective Treatments for Type 1 Diabetes-The TrialNet Experience. Carla J. Greenbaum, Cate Speake, Jeffrey Krischer, Jane Buckner, Peter A. Gottlieb, Desmond A. Schatz, Kevan C. Herold, Mark A. Atkinson. Diabetes. 2018 Jul 1;67(7):1216-1225. doi: 10.2337/db18-0065. Epub 2018 May 16.
PubMed PMID: 29769238. PMCID: PMC6014559.

Type 1 Diabetes TrialNet: A Multifaceted Approach to Bringing Disease-Modifying Therapy to Clinical Use in Type 1 Diabetes.
Polly J. Bingley, Diane K. Wherrett, Ann Shultz, Lisa E. Rafkin-Mervis, Mark A. Atkinson, Carla J. Greenbaum.
Diabetes Care. 2018 Apr 1;41(4):653-661. doi: 10.2337/dc17-0806. Epub 2018 Mar 20.
PubMed PMID: 29559451. PMCID: PMC5860837.

TCF7L2 Genetic Variants Contribute to Phenotypic Heterogeneity of Type 1 Diabetes.
Maria J. Redondo, Susan M. Geyer, Andrea K. Steck, Jay M. Sosenko, Mark S. Anderson, Peter Antinozzi, Aaron W. Michels, John M. Wentworth, Ping Xu, Alberto Pugliese, and the Type 1 Diabetes TrialNet Study Group.Diabetes Care. 2018 Feb 1;41(2):311-317. doi: 10.2337/dc17-0961. Epub 2017 Oct 12.
PubMed PMID: 29025879. PMCID: PMC5780048.

Loss of B-Cell Anergy in Type 1 Diabetes Is Associated With High-Risk HLA and Non-HLA Disease Susceptibility Alleles.
Mia J. Smith, Marynette Rihanek, Clive Wasserfall, Clayton E. Mathews, Mark A. Atkinson, Peter A. Gottlieb, John C. Cambier. Diabetes. 2018 Apr 1;67(4):697-703. doi: 10.2337/db17-0937. Epub 2018 Jan 17.
PubMed PMID: 29343548. PMCID: PMC5860860.

2017

Effect of Oral Insulin on Prevention of Diabetes in Relatives of Patients With Type 1 Diabetes: A Randomized Clinical Trial.
Writing Committee for the Type 1 Diabetes TrialNet Oral Insulin Study Group, Jeffrey P. Krischer, Desmond A. Schatz, Brian N. Bundy, Jay S. Skyler, Carla J. Greenbaum.
The Journal of the American Medical Association. 2017 Nov 21;318(19):1891-1902. doi: 10.1001/jama.2017.17070.
PubMed PMID: 29164254. PMCID: PMC5798455.

Dysglycemia and Index60 as Prediagnostic End Points for Type 1 Diabetes Prevention Trials.
Brandon M. Nathan, David C. Boulware, Susan M. Geyer, Mark A. Atkinson, Peter Colman, Robin Goland, William Russell, John M. Wentworth, Darrell M. Wilson, Carmella Evans-Molina, Diane K. Wherrett, Jay S. Skyler, Antoinette M. Moran, Jay M. Sosenko, and the Type 1 Diabetes TrialNet and Diabetes Prevention Trial–Type 1 Study Groups.
Diabetes Care. 2017 Nov 1;40(11):1494-1499. doi: 10.2337/dc17-0916. Epub 2017 Aug 31.
PubMed PMID: 28860125. PMCID: PMC5652585.

Impact of Blood Collection and Processing on Peripheral Blood Gene Expression Profiling in Type 1 Diabetes.
Linda Yip, Rebecca Fuhlbrigge, Mark A. Atkinson, C. Garrison Fathman.
BMC Genomics. 2017 Aug 18;18(1):636. doi: 10.1186/s12864-017-3949-2. Epub 2017 Aug 18.
PubMed PMID: 28821222. PMCID: PMC5563008.

2016

Tissue Distribution and Clonal Diversity of the T and B cell Repertoire in Type 1 Diabetes.
Howard R. Seay, Erik Yusko, Stephanie J. Rothweiler, Lin Zhang, Amanda L. Posgai,1 Martha Campbell-Thompson, Marissa Vignali, Ryan O. Emerson, John S. Kaddis, Dave Ko, Maki Nakayama, Mia J. Smith, John C. Cambier, Alberto Pugliese, Mark A. Atkinson, Harlan S. Robins, and Todd M. Brusko.
JCI Insight. 2016 Dec 8;1(20):e88242. doi: 10.1172/jci.insight.88242.
PubMed PMID: 27942583. PMCID: PMC5135280.

2015

Defining Pathways for Development of Disease-Modifying Therapies in Children with Type 1 Diabetes: A Consensus Report.
Diane K. Wherrett, Jane L. Chiang, Alan M. Delamater, Linda A. DiMeglio, Stephen E. Gitelman, Peter A. Gottlieb, Kevan C. Herold, Daniel J. Lovell, Trevor J. Orchard, Christopher M. Ryan, Desmond A. Schatz, David S. Wendler, Carla J. Greenbaum, the Type 1 Diabetes TrialNet Study Group.
Diabetes Care. 2015 Oct 1;38(10):1975-1985. doi: 10.2337/dc15-1429. Epub 2015 Sep 24.
PubMed PMID: 26404927. PMCID: PMC4876737.

2014

Distribution of C-Peptide and its Determinants in North American Children at Risk for Type 1 Diabetes.
Ping Xu, Xiaoning Qian, Desmond A. Schatz, David D. Cuthbertson, Jeffrey P. Krischer, the DPT-1 Study Group.
Diabetes Care. 2014 Jul 1;37(7):1959-1965. doi: 10.2337/dc13-2603. Epub 2014 Apr 23.
PubMed PMID: 24760262. PMCID: PMC4067394.

B-Lymphocyte Depletion with Rituximab and β-Cell Function: Two-Year Results.
dMark D. Pescovitz, Carla J. Greenbaum, Brian N. Bundy, Dorothy J. Becker, Stephen E. Gitelman, Robin Goland, Peter A. Gottlieb, Jennifer B. Marks, Antoinette M. Moran, Philip Raskin, Henry Rodriguez, Desmond A. Schatz, Diane K. Wherrett, Darrell M. Wilson, Jeffrey P. Krischer, Jay
S. Skyler, the Type 1 Diabetes TrialNet Anti-CD20 Study Group.
Diabetes Care. 2014 Feb 1;37(2):453-459. doi: 10.2337/dc13-0626. Epub 2013 Sep 11.
PubMed PMID: 24026563. PMCID: PMC3898764.

2013

Costimulation Modulation with Abatacept in Patients with Recent-Onset type 1 Diabetes: Follow-Up 1 Year after Cessation of Treatment.
Tihamer Orban, Brian N. Bundy, Dorothy J. Becker, Linda A. DiMeglio, Stephen E. Gitelman, Robin Goland, Peter A. Gottlieb, Carla J. Greenbaum, Jennifer B. Marks, Roshanak Monzavi, Antoinette M. Moran, Mark A. Peakman, Philip Raskin, William E. Russell, Desmond A. Schatz, Diane K. Wherrett, Darrell M. Wilson, Jeffrey P. Krischer, Jay S. Skyler, the Type 1 Diabetes TrialNet Abatacept Study Group. Diabetes Care. 2014 Apr 1;37(4):1069-1075. doi: 10.2337/dc13-0604. Epub 2013 Dec 2.
PubMed PMID: 24296850. PMCID: PMC3964491.

The Prediction of Type 1 Diabetes by Multiple Autoantibody Levels and Their Incorporation Into an Autoantibody Risk Score in Relatives of Type 1 Diabetic Patients.
Jay M. Sosenko, Jay S. Skyler, Jerry P. Palmer, Jeffrey P. Krischer, Liping Yu, Jeffrey L. Mahon, Craig A. Beam, David C. Boulware, Lisa E. Rafkin-Mervis, Desmond A. Schatz, George S. Eisenbarth, the Type 1 Diabetes TrialNet and the Diabetes Prevention Trial–Type 1 Study Groups.
Diabetes Care. 2013 Sep 1;36(9):2615-2620. doi: 10.2337/dc13-0425. Epub 2013 Jul 1.
PubMed PMID: 23818528. PMCID: PMC3747899.

Interleukin-1 Antagonism in Type 1 Diabetes of Recent Onset: Two Multicentre, Randomised, Double-Blind, Placebo-Controlled Trials. Antoinette M. Moran, Brian N. Bundy, Dorothy J. Becker, Linda A. DiMeglio, Stephen E. Gitelman, Robin Goland, Carla J. Greenbaum, Kevan C. Herold, Jennifer B. Marks, Philip Raskin, Srinath Sanda, Desmond A. Schatz, Diane K. Wherrett, Darrell M. Wilson, Jeffrey P. Krischer, Jay S. Skyler, for the Type 1 Diabetes TrialNet Canakinumab Study Group, Linda Pickersgill, Eelco de Koning, Anette-G Ziegler, Bernhard Böehm, Klaus Badenhoop, Nanette Schloot, Jens Friis Bak, Paolo Pozzilli, Didac Mauricio, Marc Y Donath, Luis Castaño, Ana Wägner, Hans Henrik Lervang, Hans Perrild, Thomas Mandrup-Poulsen,
for the AIDA Study Group.
The Lancet. 2013 Jun 1;381(9881):1905-1915. doi: 10.1016/S0140-6736(13)60023-9. Epub 2013 Apr 5.
PubMed PMID: 23562090. PMCID: PMC3827771.

2012

Performance of HbA1c as an Early Diagnostic Indicator of Type 1 Diabetes in Children and Youth.
Kendra Vehik, David D. Cuthbertson, David C. Boulware, Craig A. Beam, Henry Rodriguez, Laurent Legault, Mila Hyytinen, Marian J. Rewers, Desmond A. Schatz, Jeffrey P. Krischer, TEDDY, TRIGR, Diabetes Prevention Trial–Type 1, and Type 1 Diabetes TrialNet Natural History Study Groups.
Diabetes Care. 2012 Sep 1;35(9):1821-1825. doi: 10.2337/dc12-0111 . Epub 2012 Jun 14.
PubMed PMID: 22699293. PMCID: PMC3425003.

2011

A Longitudinal Study of GAD65 and ICA512 Autoantibodies During the Progression to Type 1 Diabetes in Diabetes Prevention Trial-Type 1
(DPT-1) Participants.
Jay M. Sosenko, Jay S. Skyler, Jerry P. Palmer, Jeffrey P. Krischer, David D. Cuthbertson, Liping Yu, Desmond A. Schatz, Tihamer Orban, George S. Eisenbarth, and Diabetes Prevention Trial–Type 1 and Type 1 Diabetes TrialNet Study Groups.
Diabetes Care. 2011 Nov 1;34(11):2435-2437. doi: 10.2337/dc11-0981. Epub 2011 Sep 12.
PubMed PMID: 21911777. PMCID: PMC3198298.

Development of Autoantibodies in the TrialNet Natural History Study.
Kendra Vehik, Craig A. Beam, Jeffrey L. Mahon, Desmond A. Schatz, Michael J. Haller, Jay M. Sosenko, Jay S. Skyler, Jeffrey P. Krischer, and for the TrialNet Natural History Study Group.
Diabetes Care. 2011 Sep 1;34(9):1897-1901. doi: 10.2337/dc11-0560. Epub 2011 Jul 12.
PubMed PMID: 21750277. PMCID: PMC3161292.

Co-Stimulation Modulation with Abatacept in Patients with Recent-Onset Type 1 Diabetes: A Randomised, Double-Blind, Placebo-Controlled Trial.
Tihamer Orban, Brian N. Bundy, Dorothy J. Becker, Linda A. DiMeglio, Stephen E. Gitelman, Robin Goland, Peter A. Gottlieb, Carla J. Greenbaum, Jennifer B. Marks, Roshanak Monzavi, Antoinette M. Moran, Philip Raskin, Henry Rodriguez, William E. Russell, Desmond A. Schatz, Diane K. Wherrett, Darrell M. Wilson, Jeffrey P. Krischer, Jay S. Skyler, and the Type 1 Diabetes TrialNet Abatacept Study Group.
The Lancet. 2011 Jul 30;378(9789):412-419. doi: 10.1016/S0140-6736(11)60886-6. Epub 2011 Jun 28.
PubMed PMID: 21719096. PMCID: PMC3462593.

Antigen-Based Therapy with Glutamic Acid Decarboxylase (GAD) Vaccine in Patients with Recent-Onset Type 1 Diabetes: a Randomised Double-Blind Trial.
Diane K. Wherrett, Brian N. Bundy, Dorothy J. Becker, Linda A. DiMeglio, Stephen E. Gitelman, Robin Goland, Peter A. Gottlieb, Carla J. Greenbaum, Kevan C. Herold, Jennifer B. Marks, Roshanak Monzavi, Antoinette M. Moran, Tihamer Orban, Jerry P. Palmer, Philip Raskin, Henry Rodriguez, Desmond A. Schatz, Darrell M. Wilson, Jeffrey P. Krischer, Jay S. Skyler, the Type 1 Diabetes TrialNet GAD Study Group. The Lancet. 2011 Jul 23;378(9788):319-327. doi: 10.1016/S0140-6736(11)60895-7. Epub 2011 Jun 27.
PubMed PMID: 21714999. PMCID: PMC3580128.

Long-Term Outcome of Individuals Treated with Oral Insulin: Diabetes Prevention Trial-Type 1 (DPT-1) Oral Insulin Trial.
Kendra Vehik, David D. Cuthbertson, Holly Ruhlig, Desmond A. Schatz, Mark A. Peakman, Jeffrey P. Krischer, and for the DPT-1 and TrialNet Study Groups.
Diabetes Care. 2011 Jul 1;34(7):1585-1890. doi: 10.2337/dc11-0523. Epub 2011 May 24.
PubMed PMID: 21610124. PMCID: PMC3120180.

Islet Autoantibody Seroconversion in the DPT-1 Study: Justification for Repeat Screening Throughout Childhood.
Kendra Vehik, Michael J. Haller, Craig A. Beam, Desmond A. Schatz, Diane K. Wherrett, Jay M. Sosenko, Jeffrey P. Krischer, and DPT-1 Study Group.
Diabetes Care. 2011 Feb 1;34(2):358-362. doi: 10.2337/dc10-1494. Epub 2011 Jan 26.
PubMed PMID: 21270193. PMCID: PMC3024349.

2010

Failure to Preserve Beta-Cell Function with Mycophenolate Mofetil and Daclizumab Combined Therapy in Patients with New- Onset Type 1 Diabetes.
Peter A. Gottlieb, Scott Quinlan, Heidi Krause-Steinrauf, Carla J. Greenbaum, Darrell M. Wilson, Henry Rodriguez, Desmond A. Schatz, Antoinette M. Moran, John M. Lachin, Jay S. Skyler, for the Type 1 Diabetes TrialNet MMF/DZB Study Group.
Diabetes Care. 2010 Apr 1;33(4):826-832. doi: 10.2337/dc09-1349. Epub 2010 Jan 12.
PubMed PMID: 20067954. PMCID: PMC2845036.

2009

Rituximab, B-Lymphocyte Depletion, and Preservation of Beta-Cell Function.
Mark D. Pescovitz, Carla J. Greenbaum, Heidi Krause-Steinrauf, Dorothy J. Becker, Stephen E. Gitelman, Robin Goland, Peter A. Gottlieb, Jennifer B. Marks, Paula F. McGee, Antoinette M. Moran, Philip Raskin, Henry Rodriguez, Desmond A. Schatz, Diane K. Wherrett, Darrell M. Wilson, John M. Lachin, Jay S. Skyler, for the Type 1 Diabetes TrialNet Anti-CD20 Study Group.
The New England Journal of Medicine. 2009 Nov 26;361(22):2143-2152. doi: 10.1056/NEJMoa0904452.
PubMed PMID: 19940299.

Pancreatic Islet Autoantibodies as Predictors of Type 1 Diabetes in the Diabetes Prevention Trial-Type 1.
Tihamer Orban, Jay M. Sosenko, David D. Cuthbertson, Jeffrey P. Krischer, Jay S. Skyler, Richard Jackson, Liping Yu, Jerry P. Palmer, Desmond A. Schatz, George S. Eisenbarth, and for the Diabetes Prevention Trial–Type 1 Study Group.
Diabetes Care. 2009 Dec 1;32(12):2269-2274. doi: 10.2337/dc09-0934. Epub 2009 Sep 9.
PubMed PMID: 19741189. PMCID: PMC2782989.

Participant and Parent Experiences in the Oral Insulin Study of the Diabetes Prevention Trial for Type 1 Diabetes.
Suzanne B. Johnson,  Amy E. Baughcum,  Lisa E. RafkinMervis,  Desmond A. Schatz,  DPT1 Study Group.
Pediatric Diabetes. 2009 May 1;10(3):177-183. doi: 10.1111/j.1399-5448.2008.00463.x. Epub 2008 Sep 24.
PubMed PMID: 18823410. PMCID: PMC4206940.

2007

Participant and Parent Experiences in the Parenteral Insulin Arm of the Diabetes Prevention Trial for Type 1 Diabetes.
Suzanne B. Johnson, Amy E. Baughcum, Korey Hood, Lisa E. Rafkin-Mervis, Desmond A. Schatz, and for the DPT-1 Study Group.
Diabetes Care. 2007 Sep 1;30(9):2193-2198. doi: 10.2337/dc06-2422 . Epub 2007 Jun 11.
PubMed PMID: 17563348.

2006

Specific Human Leukocyte Antigen DQ Influence on Expression of Antiislet Autoantibodies and Progression to Type 1 Diabetes.
Maria J. Redondo, Sunanda Babu, Adina Zeidler, Tihamer Orban, Liping Yu, Carla J. Greenbaum, Jerry P. Palmer, David D. Cuthbertson, George S. Eisenbarth, Jeffrey P. Krischer, Desmond A. Schatz.
The Journal of Clinical Endocrinology & Metabolism. 2006 May 1;91(5):1705-1713. doi: 10.1210/jc.2005-1695. Epub 2006 Feb 7.
PubMed PMID: 16464953.

2005

High Frequency of Abnormal Glucose Tolerance in DQA1*0102/DQB1*0602 Relatives Identified as part of the Diabetes Prevention Trial–Type 1 Diabetes.
Carla J. Greenbaum, George S. Eisenbarth, Mark A. Atkinson, Liping Yu, Sunanda Babu, Desmond A. Schatz, Adina Zeidler, Tihamer Orban, Clive Wasserfall, David D. Cuthbertson, Jeffrey P. Krischer, DPT-1 Study Group.
Diabetologia. 2005 Jan 1;48(1):68-74. doi: 10.1007/s00125-004-1608-z. Epub 2004 Dec 16.
PubMed PMID: 15602651.

2003

Screening Strategies for the Identification of Multiple Antibody-Positive Relatives of Individuals with Type 1 Diabetes.
Jeffrey P. Krischer, David D. Cuthbertson, Liping Yu, Tihamer Orban, Noel Maclaren, Richard Jackson, William E. Winter, Desmond A. Schatz, Jerry P. Palmer, George S. Eisenbarth.
The Journal of Clinical Endocrinology & Metabolism. 2003 Jan 1;88(1):103-108. doi: 10.1210/jc.2002-020760.
PubMed PMID: 12519837.

2001

First-Phase Insulin Release During the Intravenous Glucose Tolerance Test as a Risk Factor for Type 1 Diabetes.
H. Peter Chase, David D. Cuthbertson, Lawrence M. Dolan, Francine Kaufman, Jeffrey P. Krischer, Desmond A. Schatz, Neil H. White, Darrell M. Wilson, Joseph I. Wolfsdorf, the Diabetes Prevention Trial–Type 1 Study Group.
The Journal of Pediatrics. 2001 Feb 1;138(2):244-249. doi: 10.1067/mpd.2001.111274.
PubMed PMID: 11174623.

2000

Islet Cell Antibody-Positive Relatives with Human Leukocyte Antigen DQA1*0102, DQB1*0602: Identification by the Diabetes Prevention Trial-Type 1
Carla J. Greenbaum, Desmond A. Schatz, David D. Cuthbertson, Adina Zeidler, George S. Eisenbarth, Jeffrey P. Krischer. The Journal of Clinical Endocrinology & Metabolism. 2000 Mar 1;85(3):1255-1260. doi: 10.1210/jcem.85.3.6459. PubMed PMID: 10720072.